Default HTG hotel image

Find hotels in Santa Cruz from CA $83

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Sep 17 - Sep 18
Tomorrow
Sep 18 - Sep 19
This weekend
Sep 18 - Sep 20
Next weekend
Sep 25 - Sep 27

Filter by

Star rating

Guest rating

Our top choices for Santa Cruz hotels

1. Motel San Luis de Nogales

Motel San Luis de Nogales
Nogales
United States
Priscilla
CA $69
CA $83 total
includes taxes & fees
Sep 18 - Sep 19
Motel San Luis de Nogales

2. City Express by Marriott Cananea

City Express by Marriott Cananea
Cananea
United States
Osborn
CA $117
CA $130 total
includes taxes & fees
Oct 4 - Oct 5
City Express by Marriott Cananea

3. Fiesta Inn Nogales

Fiesta Inn Nogales
Nueva Nogales
United States
Mario
CA $113
CA $137 total
includes taxes & fees
Sep 19 - Sep 20
Fiesta Inn Nogales

4. Fairfield Inn & Suites by Marriott Nogales

Fairfield Inn & Suites by Marriott Nogales
Nogales
United States
David
CA $154
CA $171 total
includes taxes & fees
Sep 26 - Sep 27
Fairfield Inn & Suites by Marriott Nogales

5. Hotel Marques De Cima

Hotel Marques De Cima
Nogales
United States
martin
CA $132
CA $148 total
includes taxes & fees
Sep 23 - Sep 24
Hotel Marques De Cima

6. Hotel Fray Marcos

Hotel Fray Marcos
Nogales
United States
Viet
CA $126
CA $140 total
includes taxes & fees
Sep 20 - Sep 21
Hotel Fray Marcos

7. Hotel Pedregal

Hotel Pedregal
Nogales
United States
Idaliee
CA $112
CA $133 total
includes taxes & fees
Sep 20 - Sep 21
Hotel Pedregal

8. City Express by Marriott Nogales

City Express by Marriott Nogales
Nogales
United States
Carlos
CA $110
CA $122 total
includes taxes & fees
Oct 11 - Oct 12
City Express by Marriott Nogales
View all properties
Save an average of 15% on thousands of hotels when you're signed in

Top Santa Cruz Hotel Reviews

Hotel Fray Marcos

Hotel Fray Marcos

8/10 Good
"Like: Staff were very attentive and helpful. Rooms were clean and cool. Bathroom counter had enough space to hold hygiene items. Housekeeping was very attentive as well. Restaurant was good, highly recommend trying the chili rellenos and flan. Even though valet parking was a few blocks over, it was gated and had someone there also. I drove my own vehicle and left it parked there, my entire stay (four days). In walking distance to the border, restaurants, shops. Dislikes: The parking not being "on-site." Not wheelchair accessible at entrance or in lobby. To get to the rooms you need to walk up stairs and then more stairs or a very small elevator (which I believe is for staff only). Bathroom was very tight, small. You opened up the shower door to sink. This bathroom was made, for one person at a time (I had a double bedroom). I recommend trying this hotel for it's great service, location and it's history. Older building with beautiful wood floors and decor. Enjoy!"
Veronica 3-night trip
Posted 2 hours ago
Hotel Fray Marcos
City Express by Marriott Cananea

City Express by Marriott Cananea

10/10 Excellent
"Muy tranquilo, con vistas muy hermosas hacia el lago y a la mina Buena Vista del cobre, las instalaciones del parque Tamosura, realmente muy buenas, limpias y cuidando al medio ambiente. Muy agradable estancia"
Elizabeth 4-night trip
Posted 4 hours ago
City Express by Marriott Cananea
Fiesta Inn Nogales

Fiesta Inn Nogales

8/10 Good
"Most of the staff was nice except an older woman who worked front desk. Being American I still spoke Spanish whole visit and gave pesos to everyone that helped us. Food was excellent at restaurant. And room service was excellent as well, plus it's 24hrs. Cleaning stsff came around asking if anything was needed. I gave 4 stars instead of 5 due to front desk older woman. She refused to help me and told someone else to help due to me only speaking English. As stated I spoke Spanish whole visit being fluent though I'm American."
Patience 1-night trip
Posted 2 days ago
Fiesta Inn Nogales
Hotel Pedregal

Hotel Pedregal

10/10 Excellent
"A great experience at a price you'll never find in the US or at least in california. The rooms are very spacious and have everything up to date including a smart TV with cable, microwave, air conditioner, and refrigerator. The overall architecture is very high end and you get your own carport with no garage door but the hotel has a main gate and is very safe inside the property. I rarely ever need a hotel but if I ever end up in Nogales sonora again this is definitely gonna be my go to hotel. The staff also accepts US dollars or Mexican pesos."
Felipe 1-night trip
Posted 2 months ago
Hotel Pedregal
Motel San Luis de Nogales

Motel San Luis de Nogales

10/10 Excellent
"The view is nice.A lot of stores around you a great restaurant downstairs. Kid friendly too."
Priscilla 2-night trip
Posted 2 months ago
Motel San Luis de Nogales
Charming 2-bedroom house with WiFi, AC in beautiful Cananea

Charming 2-bedroom house with WiFi, AC in beautiful Cananea

10/10 Excellent
"Nice place. Very friendly and helpful host. Thank you."
Kendall 3-night trip
Posted 4 months ago
Charming 2-bedroom house with WiFi, AC in beautiful Cananea

More cheap stays in Santa Cruz

Hotel Pedregal

Hotel Pedregal

Av. del Yaqui Colinas del Yaqui Nogales Son.
CA $112
CA $133 total
Sep 20 - Sep 21
includes taxes & fees
8.2/10 Very good! (63 reviews)
Hotel Pedregal
Hotel Marques De Cima

Hotel Marques De Cima

Av. Alvaro Obregon # 2024 Nogales SON
CA $132
CA $148 total
Sep 23 - Sep 24
includes taxes & fees
Hotel Marques De Cima
Hotel Plaza Nogales

Hotel Plaza Nogales

Prolongacion Av.Alvaro Obregon 4190 Col. Nuevo Nogales Nogales SON
Get ratesHotel Plaza Nogales

Frequently asked questions

What is the best area to stay in Santa Cruz?
The best area to stay in Santa Cruz, Sonora, is the town centre, particularly around the main square, Plaza Zaragoza.This area is the heart of Santa Cruz, offering a convenient base for exploring. You'll find many of the town's key landmarks, including the historic Templo de Nuestra Señora de Guadalupe, within easy walking distance. The streets here are generally well-maintained and offer a pleasant stroll amongst local shops and eateries.Couples looking for a relaxed and authentic experience will find the town centre ideal. It provides opportunities to enjoy local cuisine, browse artisan crafts, and simply soak in the local way of life without needing to travel far. The evenings around Plaza Zaragoza often feature local gatherings, adding to the pleasant atmosphere.
When is the best time to go to Santa Cruz?
The best time to visit Santa Cruz, Sonora, Mexico is during the cooler, drier months from November to April.During this period, the weather is pleasantly warm with average temperatures ranging from 20°C to 28°C, and there's very little rainfall. This makes it ideal for exploring the outdoors, whether you're interested in hiking the Sierra Azul mountains or enjoying the local markets without the intense heat of summer.Couples looking for a relaxed getaway will appreciate the comfortable climate for leisurely strolls through the town's historic centre, perhaps visiting the Mission de Santa Cruz. The evenings are mild, superb for dining al fresco.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Santa Cruz.
How much is the nightly rate at a Santa Cruz hotel?
Prices for hotels in Santa Cruz often vary, but you can find a great deal from CA $83 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

Explore a world of travel with Expedia